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EASI-Genomics is a European Genomics Infrastructure Horizon 2020 project. This novel infrastructure supports researchers in next-generation sequencing and other high-end genomics applications and genomic data analysis. The infrastructure is accessible worldwide to researchers from both Academia and the Industry. EASI-Genomics invites external users to apply for access by opening several calls for proposals. Academic research groups and scientific institutions are highly encouraged to submit projects collaborating with SMEs.